Genes lost during the transition from land to water in cetaceans highlight genomic changes associated with aquatic adaptations

The ancestors of modern cetaceans (whales, dolphins, and porpoises) transitioned from a terrestrial to a fully aquatic lifestyle during the Eocene about 50 million years ago. This process constitutes one of the most marked macroevolutionary transitions in mammalian history and was accompanied by profound anatomical, physiological, and behavioral transformations that allowed cetaceans to adapt and thrive in the novel habitat.

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